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At the end 2007, the Tufts Center for the Study of Drug Development estimated that approximately 43 percent of all US-regulated clinical trials are now conducted outside of the United States (Source: Boston Globe December 29, 2007). In the coming years, industry experts expect this percentage to accelerate as the search continues for more targeted patient populations, more treatment naïve patients, lower cost sites, and broader market penetration.
The attached PDF Country List shows a partial directory (effective January 1, 2008) of the countries in which the payment of invoices, by clinical trial sponsors for professional services and materials as related to clinical trial projects, are subject to VAT and other tax related assessments. Each county has specific national laws as to what expense categories fall under the VAT and related tax laws, and how much are the specific tax rates to be applied. Clinical VAT Recovery Services provides professional tax structure and model advisement to sponsors to legally minimize and/or recapture these taxes on an international country-by-country basis.
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